A fully digital, objective, and patient-friendly assessment platform for measuring ataxia severity through smart devices
No human examiner needed
Digital features are sensitive to change
Motor, cognitive/executive & PROs
Following established methodologies
Existing scales lack fine-grained sensitivity and rely heavily on clinician judgment. DASS provides objective, automated measurements.
Assesses motor function, fine motor skills, cognition, speech, and patient-reported outcomes in one integrated platform.
Built for sensitivity to change with validated methodology, making it ideal for clinical trials and longitudinal studies.
Participants complete 10 active tasks using smartphones/tablets with IMU sensors and video capture
Comprehensive PROs covering gait, cognition, mood, and daily function
Automated derivation of hundreds of digital features from sensor data
Factor analysis combines features into a validated severity score
All sites begin assessments with regular coordination meetings
Statistical analysis and DASS score development
Clinical validation and integration into research trials
Jennifer Faber
DZNE Bonn
Philipp Wegner
DZNE Bonn
German Center for
Neurodegenerative Diseases (DZNE)
Bonn, Germany